Bacteriophage Dietary Supplements/Prebiotics/Probiotics/Nutraceuticals

Phages can gently modulate the human microbiome for improved health outcomes

Phages as dietary supplements

One of the most exciting applications of bacteriophages lies in their use as dietary supplements to precisely fine-tune the human microbiome - including the gastrointestinal (GI) tract, as well as the vaginal, oral, and skin microbiomes. Unlike broad-spectrum antibiotics, which can disrupt the entire microbial community and contribute to antibiotic resistance or secondary infections, bacteriophages offer a highly targeted approach. They selectively infect and lyse specific bacterial strains while leaving beneficial microbes intact. This precision makes phages ideal for gently fine-tuning microbiome for various health benefits. Intralytix has pioneered this field with its patented PhageBiotix™ platform, which employs lytic bacteriophages to to target and control unwanted bacterial species in the GI tract, oral cavity, vagina, and skin, preventing potential imbalances that could affect overall health and wellbeing. These formulations exert a gentle, selective influence on the overall microflora, enhancing protective effects while minimizing unintended disruptions. Furthermore, PhageBiotix™ products are fully compatible - and often synergistic - with traditional bacteria-based or yeast-based probiotics, enabling the creation of the SuperBiotix™ line. These advanced dietary supplements combine conventional probiotic cultures with PhageBiotix™ phage preparations, amplifying health benefits through a dual-action mechanism: traditional probiotics replenish beneficial bacteria or yeast populations, while phages specifically target harmful bacteria. This innovative approach reflects Intralytix's core philosophy of harnessing natural lytic phages for microbiome modulation, embodied in the principles of Safety By Nature™ and Wellness By Phage™.

Intralytix offers a range of bacteriophage-based dietary supplement products specifically designed to support various targeted health benefits.

These products are typically supplied as dried formulations with a shelf life of 24 months or longer when stored at room temperature in their original, unopened containers. Concentrated aqueous solutions are also available upon request. Some of these innovative products are listed below. In addition, custom phage formulations can be readily developed and produced to meet specific customer needs and application goals. For more information on these products or designing phage formulations for other health benefits, please contact us at info@intralytix.com.

ShigActive™

Targets Shigella species in the gastrointestinal tract. This product is in development

U.S. Patent Application No. 15/002,708; International Patent Application No. PCT/US2016/014308; Bangladesh Patent Application No. 17/2016. Other patent applications pending.