Intralytix Receives FDA CVM Approval for Salmonella-Targeting Phage Preparation for Use in Pet Food Applications

Columbia, MD – September 30, 2025 – Intralytix, Inc., a global leader in bacteriophage technology, announced today that it has received formal approval from the U.S. Food and Drug Administration’s Center for Veterinary Medicine (FDA CVM) for its Salmonella-specific bacteriophage preparation for use as a processing aid to help control S. enterica in pet food and ingredients for use in pet food. The approval was granted as an affirmation of the GRAS (Generally Recognized as Safe; AGRN 74) status by the FDA CMV. This landmark approval marks the first time a bacteriophage product has been authorized by CVM for reducing Salmonella in pet food and pet food ingredients.

The newly approved product, SalmoLyze™, developed and manufactured by Intralytix, is designed to significantly reduce or eliminate Salmonella contamination in pet food and pet food ingredients, helping manufacturers comply with food safety regulations while enhancing animal
Dr. Alexander “Sandro” Sulakvelidze, President and CEO of Intralytix and public health.

"This is a major milestone not just for Intralytix, but for the broader pet food industry and the field of bacteriophage technology," said Dr. Alexander “Sandro” Sulakvelidze, President and Chief Executive Officer of Intralytix. “The FDA CVM approval validates the safety and effectiveness of phage-based interventions and paves the way for expanding the use of our eco-friendly, natural antimicrobial products to improve food safety in the pet food sector. It is also a strong testament to the innovation, dedication, and scientific excellence of the Intralytix team, whose pioneering work continues to set the standard for phage technology worldwide.”

Greg Strang, Director of the food safety Division at Intralytix, added: “Pet food manufacturers are under increasing pressure to meet stricter food safety standards, and Salmonella has long been one of the industry’s toughest challenges. With SalmoLyze™, we are providing a targeted, science-driven solution that is both effective and natural. This approval gives manufacturers a powerful new tool to protect pets, their owners, and the food supply chain.”

Greg Strang, Director of the food safety Division at IntralytixThe approval was granted following an extensive scientific review process that confirmed the product’s safety, efficacy, and consistency in targeting Salmonella spp. without disrupting beneficial microbiota or leaving chemical residues. The preparation is intended for use during various stages of pet food production, including in raw materials, during processing, or as a post-processing application.

About Intralytix, Inc.

Headquartered in Columbia, Maryland, Intralytix is the world’s leading developer of bacteriophage-based products for food safety, human health, veterinary applications, and environmental remediation. The company currently markets a range of FDA-cleared and USDA-approved phage products and maintains a robust pipeline of novel nutraceutical and therapeutic antimicrobial interventions targeting antibiotic-resistant and foodborne pathogens. For more information, please visit www.intralytix.com or contact:

Alexander Sulakvelidze
President & CEO
Intralytix, Inc.
asulakvelidze@intralytix.com
+1 (410) 625-2533