ListShield™

Phage Preparation Effective Against Listeria monocytogenes

ListShield™ is an all-natural, non-chemical antimicrobial preparation for controlling the foodborne bacterial pathogen Listeria monocytogenes. The active ingredients of ListShield™ are naturally occurring bacteriophages that selectively and specifically kill L. monocytogenes. ListShield™ is specifically designed for treating foods that are high risk for L. monocytogenes contamination. It can also be used to eliminate or significantly reduce the levels of L. monocytogenes on non-food contact equipment, surfaces, etc. in food processing plants and other food establishments. ListShield™ is ideal for use in HACCP programs that have identified L. monocytogenes control as a potential problem.

ListShield™ received a "Best of What's New" award in 2006 from Popular Science magazine.

ListShield™ is the choice for eliminating or significantly reducing contamination of food with L. monocytogenes because it:

• Complies with FDA food additive regulations, for direct application to meat and poultry products that meet the ready-to-eat definition (21 CFR § 172.785)
• Is FSIS-listed as safe and suitable for use as processing aid with no labeling requirements when applied to various ready-to-eat meat and poultry products (FSIS Directive 7120.1)
• Is GRAS for direct application to fish and shellfish (including smoked varieties; e.g., smoked salmon), fresh and processed fruits, fresh and processed vegetables, and dairy products (including cheese) (GRN No. 528)
• Is Health Canada approved for use on ready-to-eat meat and poultry, smoked salmon, fresh-cut apples, and long leaf lettuce (iLONO)
• Is National Food Service of Israel approved as a food processing aid for the treatment of ready-to-eat meat and poultry products (Ref: 70275202).
• Is certified both Kosher and Halal
• Is OMRI listed ("organic")
• Does not contain preservatives
• Is cost effective and cost competitive
• Is effective under a wide range of food storage conditions (e.g. 2°C-42°C)
• Is all natural, non-GM (genetically-modified)
• Does not alter food flavor, aroma, or nutritional value

Scientific Literature

Employing list-shield bacteriophage as a bio-control intervention for Listeria monocytogenes from raw beef surface and maintain meat quality during refrigeration storage
LWT - Food Science and Technology, 2020
Ishaq, A., P. D. Ebner, Q. A. Syed, and H. Ubaid ur Rahman.

Reduction of Listeria monocytogenes on chicken breasts by combined treatment with UV-C light and bacteriophage ListShield.
LWT, 2017
Yang, S., Sadekuzzaman, M., and Ha, S.-D.

Applicability of commercial phage-based products against Listeria monocytogenes for improvement of food safety in Spanish dry-cured ham and food contact surfaces.
Food Control, 2017
Gutiérrez, D., Rodríguez-Rubio, L., Fernández, L., Martínez, B., Rodríguez, A., and García, P.

Effectiveness of a phage cocktail as a biocontrol agent against L. monocytogenes biofilms.
Food Control, 2017
Sadekuzzaman, M., S. Yang, M. F. R. Mizan, H.-S. Kim, and S.-D. Ha.

Bacteriophage cocktail significantly reduces or eliminates Listeria monocytogenes contamination on lettuce, apples, cheese, smoked salmon and frozen foods
Food Microbiology, 2015
Perera, M., Abuladze, T., Li M., Woolston, J., and Sulakvelidze, A.

Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected Mice.
International Journal of Microbiology , 2010
Mai, V., Ukhanova, M., Visone, L., Abuladze, T., and Sulakvelidze, A.

Optimizing Concentration and Timing of a Phage Spray Application To Reduce Listeria monocytogenes on Honeydew Melon Tissue.
Journal of Food Protection, 2004
Leverentz, B., Conway, W.S., Janisiewicz, W., and Camp, M.J.

Biocontrol of Listeria monocytogenes on Fresh-Cut Produce by Treatment with Lytic Bacteriophages and a Bacteriocin.
Applied and Environmental Microbiology, 2003
Leverentz, B., Conway, W.S., Camp, M.J., Janisiewicz, W.J., Abuladze, T., Yang, M., Saftner, R., and Sulakvelidze, A.

For product inquires or to place an order, email Intralytix at sales@intralytix.com or call 1-877-ITXPHAGE (489-7424) and select option 1.

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